Strong painkiller tramadol is used to treat moderate to severe pain that is not being treated by other
painkillers. A synthetic opioid, tramadol operates on the brain and spine (central nervous system) to
lessen pain perception.
Tramadol is available in an extended-release formulation for the continuous management of pain.
Tramadol in this form should not be used to treat pain on and as-needed basis.
Tramadol reduces uptake of two neurotransmitters, norepinephrine and serotonin, in addition to
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